Should I override DefaultUrlHost?

I get the following message after save an edit:

Access check on Main failed. Action "redirect": unsafe redirect to https://my.vhost.com/Main/WebTopBar: host does not match {DefaultUrlHost} , and is not in {PermittedRedirectHostUrls} http://my.vhost.com".

The save succeeds, but I would like to understand if I need to override these two variables in a virtual host config file somewhere or this is just my naivete in setting this up. Thanks.

-- DaveHayes - 07 Nov 2010